Abbasi MA, Mahdavi AH, Samie AH & Jahanian R. 2014. Effects of different levels of dietary crude protein and threonine on performance, humoral immune responses, and intestinal morphology of broiler chicks. Brazilian Journal of Poultry Science, 16: 35-44. DOI: 10.1590/S1516-635X2014000100005
Azzam MMM & El-Gogary MR. 2015. Effects of dietary threonine levels and stocking density on the performance, metabolic status and immunity of broiler chickens. Asian Journal of Animal and Veterinary Advances, 10: 215-225. DOI: 10.3923/ajava.2015.215.225
Azzam MMM, Zou XT, Dong XY & Xie P. 2012. Influence of L–threonine supplementation on goblet cell numbers, histological structure and antioxidant enzyme activities of laying hens reared in a hot and humid climate. British Poultry Science, 53: 640–645. DOI: 10.1080/00071668.2012.726707
Basmacioğlu Malayoğlu H, Baysal Ş, Misirlioğlu Z, Polat M, Yilmaz H & Turan N. 2010. Effects of oregano essential oil with or without feed enzymes on growth performance, digestive enzyme, nutrient digestibility, lipid metabolism and immune response of broilers fed on wheat–soybean meal diets. British Poultry Science, 51: 67-80. DOI: 10.1080/00071660903573702
Bedford MR. 1993. Mode of Action of Feed Enzymes. Journal of Applied Poultry Research, 2: 85–92. DOI: 10.1093/japr/2.1.85
Biloni A, Quintana CF, Menconi A, Kallapura G, Latorre J, Pixley C, Layton S, Dalmagro M, Hernandez-Velasco X, Wolfenden A, Hargis BM & Tellez G. 2013. Evaluation of effects of EarlyBird associated with FloraMax-B11 on Salmonella Enteritidis, intestinal morphology, and performance of broiler chickens. Poultry Science, 92: 2337–2346. DOI: 10.3382/ps.2013-03279
Chen YP, Cheng YF, Li XH, Yang WL, Wen C, Zhuang S & Zhou YM. 2016. Effects of threonine supplementation on the growth performance, immunity, oxidative status, intestinal integrity, and barrier function of broilers at the early age. Poultry Science, 96: 405–413. DOI: 10.3382/ps/pew240
Choct M, Hughes RJ, Trimble RP, Angkanaporn K & Annison G. 1995. Non-starch polysaccharide-degrading enzymes increase the performance of broiler chickens fed wheat of low apparent metabolizable energy. Journal of Nutrition, 125: 485–492. DOI: 10.1093/jn/125.3.485
Corzo A, Kidd MT, Dozier WA, Pharr GT & Koutsos EA. 2007. Dietary threonine needs for growth and immunity of broiler raised under different litter conditions. Journal of Applied Poultry Research, 16: 574-582. DOI: 10.3382/japr.2007-00046
de Barros Moreira Filho AL, de Oliveira CJ, de Oliveira HB, Campos DB, Guerra RR, Costa FG & Givisiez PE. 2015. High incubation temperature and threonine dietary level improve ileum response against post-hatch salmonella enteritidis inoculation in broiler chicks. PLOS ONE, 10: e0131474. DOI: 10.1371/journal.pone.0131474
Defa L, Changting X, Shiyan Q, Jinhui Z, Johnson EW & Thacker PA. 1999. Effects of dietary threonine on performance, plasma parameters and immune function of growing pigs. Animal Feed Science and Technology, 78: 179–188. DOI: 10.1016/S0377-8401(99)00005-X
Dibaiee-nia G, Akbari MR & Karimi S. 2017. Effects of Supplemental Zinc in a Wheat-Based Diet on Performance, Intestinal Viscosity, Immune System and Lipid Peroxidation of 21-Day Old Broiler Chickens. Poultry Science Journal, 5: 7-15. DOI: 10.22069/psj.2017.11072.1189
Gao F, Jiang Y, Zhou GH & Han ZK. 2007. The effects of xylanase supplementation on growth, digestion, circulating hormone and metabolite levels, immunity and gut microflora in cockerels fed on wheat-based diets. British Poultry Science, 48: 480-488. DOI: 10.1080/00071660701477320
Gonzalez-Ortiz G, Sola-Oriol D, Martinez-Mora M, Perez JF & Bedford MR. 2017. Response of broiler chickens fed wheat-based diets to xylanase supplementation. Poultry Science, 96: 2776–2785. DOI: 10.3382/ps/pex092
Gridley MF. 1960. Manual of Histologic and Special Staining Technique. 2nd Ed. McGraw-Hill. New York. 206 Pages.
Habte-Tsion HM, Ren M, Liu B, Ge X, Xie J & Chen R. 2016. Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala). Fish and Shellfish Immunology, 51: 189-199. DOI: 10.1016/j.fsi.2015.11.033
Haghighi HR, Gong J, Gyles CL, Hayes MA, Sanei B, Parvizi P, Gisavi H, Chambers JR & Sharif S. 2005. Modulation of antibody-mediated immune response by probiotics in chickens. Clinical and Diagnostic Laboratory Immunology, 12: 1387-1392. DOI: 10.1128/CDLI.12.12.1387-1392.2005
Hetland H, Choct M & Svihus B. 2004. Role of insoluble non-starch polysaccharides in poultry nutrition. World’s Poultry Science Journal, 60: 415-422. DOI: 10.1079/WPS200325
Hosseini SM, Manafi M & Nazarizadeh H. 2017. Effects of xylanase supplementation and citric acid on performance, ileal nutrients digestibility, and gene expression of intestinal nutrient transporters in broilers challenged with clostridium perfringens. Journal of Poultry Science, 54: 149-156. DOI: 10.2141/jpsa.0160099
Kalmendal R & Tauson R. 2012. Effects of a xylanase and protease, individually or in combination, and an ionophore coccidiostat on performance, nutrient utilization, and intestinal morphology in broiler chickens fed a wheat-soybean meal-based diet. Poultry Science, 91: 1387–1393. DOI: 10.3382/ps.2011-02064
Kidd MT & Kerr BJ. 1996. L-Threonine for poultry: A review. Journal of Applied Poultry Research, 5: 358-367. DOI: 10.1093/japr/5.4.358
Liu WC & Kim IH. 2016. Effects of dietary xylanase supplementation on performance and functional digestive parameters in broilers fed wheat-based diets. Poultry Science, 96: 566-573. DOI: 10.3382/ps/pew258
Min YN, Liu SG, Qu ZX, Meng GH & Gao YP. 2016. Effects of dietary threonine levels on growth performance, serum biochemical indexes, antioxidant capacities, and gut morphology in broiler chickens. Poultry Science, 96: 1290-1297. DOI: 10.3382/ps/pew393
Morel PCH, Padilla RM & Ravindran G. 2003. Effect of Non-starch Polysaccharides on Mucin Secretion and Endogenous Amino Acid Losses in Pigs. Asian-Australasian Journal of Animal Science, 16: 1332-1338. DOI: 10.5713/ajas.2003.1332
NRC (National Research Council). 1994. Nutrient Requirements of Poultry. 9th Rev. Ed. National Academy Press. Washington, DC. 176 Pages.
Pirgozliev VR, Birch CL, Ross SP, Kettlewell PS & Bedford MR. 2003. Chemical composition and the nutritive quality of different wheat cultivars for broiler chickens. British Poultry Science, 44: 464-475. DOI: 10.1080/0007166031000085594
Placer ZA, Cushman LL & Johnson BC. 1966. Estimation of product of lipid peroxidation (malonyl dialdehyde) in biochemical systems. Analytical Biochemistry, 16: 359-364. DOI: 10.1016/0003-2697(66)90167-9
Rakowska M, Rek-Ciepty B, Sot A, Lipińska E, Kubiński T, Barcz I & Afanasjew B. 1993. The effect of rye, probiotics and nisine on faecal flora and histology of the small intestine of chicks. Journal of Animal and Feed Sciences, 2: 73-81. DOI: 10.22358/jafs/69868/1993
Rhodes JM. 1989. Colonic mucus and mucosal glycoproteins: the key to colitis and cancer? Gut, 30: 1660–1666.
SAS (Statistical Analysis System). 2016. SAS/STAT® 9.4. User’s Guide. SAS Institute Inc. Cary, North Carolina.
Schaart MW, Schierbeek H, Van Der Schoor SR, Stoll B, Burrin DG, Reeds P & Van Goudoever JB. 2005. Threonine utilization is high in the intestine of piglets. Journal of Nutrition, 135: 765-770. DOI: 10.1093/jn/135.4.765
Shirzadegan K, Nickkhah I & Jafari MA. 2015. Impacts of dietary l‐threonine supplementation on performance and intestinal morphology of broiler chickens during summer time. Iranian Journal of Applied Animal Science, 5: 431-436.
Sigolo S, Zohrabi Z, Gallo A, Seidavi A & Prandini A. 2017. Effect of a low crude protein diet supplemented with different levels of threonine on growth performance, carcass traits, blood parameters, and immune responses of growing broilers. Poultry Science, 96: 2751-2760. DOI: 10.3382/ps/pex086
Smirnov A, Tako E, Ferket P & Uni Z. 2006. Mucin gene expression and mucin content in the chicken intestinal goblet cells is affected by in ovo feeding of carbohydrates. Poultry Science, 85: 669–673. DOI: 10.1093/ps/85.4.669
Smits CHM, Veldman A, Verstegen MWA & Beynen AC. 1997. Dietary carboxymethylcellulose with high instead of low viscosity reduces macronutrient digestion in broiler chickens. The Journal of Nutrition, 127: 483-487. DOI: 10.1093/jn/127.3.483
Stoll B. 2006. Intestinal uptake and metabolism of threonine: nutritional impact. Advances in Pork Production, 17: 257–263.
Stoll B, Henry J, Reeds PJ, Hung Y, Jahoor F & Burrin DG. 1998. Catabolism dominates the first-pass intestinal metabolism of dietary essential amino acids in milk protein-fed piglets. The Journal of Nutrition, 128: 606-614. DOI: 10.1093/jn/128.3.606
Taheri HR & Shirzadegan K. 2017. Multiple-enzyme supplementation on digestive traits, carcass
characteristics, blood lipid parameters and growth performance of broilers fed a wheat-based diet. Asian-Australasian Journal of Animal Science, 30: 1285-1291. DOI: 10.5713/ajas.16.0415
Tenenhouse HS & Deutsch HF. 1966. Some physical-chemical properties of chicken γ-globulins and their pepsin and papain digestion products. Immunochemistry, 3: 11–20. DOI: 10.1016/0019-2791(66)90277-1
Tizard I. 1992. Veterinary Immunology: an Introduction. 4th Ed. Saunders. Philadelphia. 498 Pages.
Viveros A, Brenes A, Pizarro M & Castario M. 1994. Effect of enzyme supplementation of a diet based on barley, and autoclave treatment, on apparent digestibility, growth performance and gut morphology of broilers. Animal Feed Science and Technology, 48: 237–251. DOI: 10.1016/0377-8401(94)90175-9
Wang W, Zeng X, Mao X, Wu G & Qiao S. 2010. Optimal dietary true ileal digestible threonine for supporting the mucosal barrier in small intestine of weanling pigs. The Journal of Nutrition, 140: 981–986. DOI: 10.3945/jn.109.118497
Wang X, Qiao S, Yin YL, Yue L, Wang Z & Wu G. 2007. A deficiency or excess of dietary threonine reduces protein synthesis in jejunum and skeletal muscle of young pigs. The Journal of Nutrition, 137: 1442-1446. DOI: 10.1093/jn/137.6.1442
Wils-Plotz EL & Dilger RN. 2013. Combined dietary effects of supplemental threonine and purified fiber on growth performance and intestinal health of young chicks. Poultry Science, 92: 726-734. DOI: 10.3382/ps.2012-02664
Zaghari M, Zaefarian F & Shivazad M. 2011. Standardized ileal digestible threonine requirements and its effects on performance and gut morphology of broiler chicks fed two levels of protein. Journal of Agricultural Science and Technology, 13: 541-552.