Follow Up of Maternally Derived Antibodies Titer against Economically Important Viral Diseases of Chicken

Document Type : Original Paper


1 Animal Health Research Division, Bangladesh Livestock Research Institute (BLRI), Savar, Dhaka-1341, Bangladesh

2 Clinical Microbiology & Infectious Medicine, Department of Medical Sciences, Uppsala University, Uppsala-75185, Sweden


The study was conducted to know the rate of maternally derived antibodies (MDAs) transfer from parents to their offspring and declining the MDAs in their chicks at 0, 7, 14, and 21 days of age against four major poultry viruses like Newcastle disease virus (NDV), Infectious bronchitis virus (IBV), Infectious bursal diseases virus (IBDV), and Avian Reo virus (ARV). The MDAs was studied on Grandparent (GP) to Parent stock (PS), and Parent stock (PS) to broiler at 30 weeks and 50 weeks of age in Cobb-500 broiler strain chicken. The MDAs was measured from serum antibody titer by indirect ELISA test. The MDAs transfer rate against NDV from GP to PS at 50 weeks of age was higher (68.82%) than at 30 weeks of age but in case of PS to broiler it was higher (66.01%) at 30 weeks of age and its persistent rate also higher (7.96%) up to 21th days of age. Against IBV, MDAs transfer rates were higher in PS to broiler than GP to PS of both ages and highest rates were revealed in PS to broiler at 30 weeks of age as 70.72%. On the other hand, among all lines MDAs transfer rates against IBDV was higher (86.94%) in GP to PS at 30 weeks of age. For ARV, the MDAs transfer rates were highest in GP to PS in both ages than PS to broiler and within GP to PS at 50 weeks of age, it was highest (94.87%) than 30 weeks of age. Accordingly, the poultry producer may help to develop an effective vaccination schedule by considering the MDAs from above experiment.


Ahmed Z & Akhter S. 2003. Role of maternal antibodies in protection against infectious bursal disease in commercial broilers. International Journal of Poultry Science, 2: 251-255. DOI: 10.3923/ijps.2003.251.255
Al-Natour MQ, Ward LA, Saif YM, Stewart-Brown B & Keck LD. 2004. Effect of diffferent levels of maternally derived antibodies on protection against infectious bursal disease virus. Avian Diseases, 48: 177-182. DOI: 10.1637/5319
Ali MZ, Rahman MM & Sultana S. 2015. Seroprevalence of Mycoplasma gallisepticum antibody by ELISA and serum plate agglutination test of laying chicken. Veterinary World,8: 9-14. DOI: 10.14202/vetworld.2015.9-14
Baron MD, Iqbal M & Nair V. 2018. Recent advances in viral vectors in veterinary vaccinology. Current Opinion in Virology, 29: 1-7. DOI: 10.1016/j.coviro.2018.02.002
BenĨina D, Narat M, Bidovec A & Zorman-Rojs O. 2005. Transfer of maternal immunoglobulins and antibodies to Mycoplasma gallisepticum and Mycoplasma synoviae to the allantoic and amniotic fluid of chicken embryos. Avian Pathology,34: 463-472. DOI: 10.1080/03079450500368011
Cavanagh DGJ. 2008. Diseases of Poultry (12 ed.): Iowa State University Press, Iowa 50014.
Chhabra R, Forrester A, Lemiere S, Awad F, Chantrey J & Ganapathy K. 2015. Mucosal, Cellular, and Humoral Immune Responses Induced by Different Live Infectious Bronchitis Virus Vaccination Regimes and Protection Conferred against Infectious Bronchitis Virus Q1 Strain. Clinical and Vaccine Immunology,22: 1050-1059. DOI: 10.1128/cvi.00368-15
Elhady MA, Ali A, Kilany WH, Elfeil WK, Ibrahim H, Nabil A, Samir A & El Sayed M. 2018. Field Efficacy of an Attenuated Infectious Bronchitis Variant 2 Virus Vaccine in Commercial Broiler Chickens. Veterinary Sciences, 5: 49. DOI: 10.3390/vetsci5020049
Gelb JJr, Wolff JB & Moran CA. 1991. Variant serotypes of infectious bronchitis virus isolated from commercial layer and broiler chickens. Avian Diseases,  35:  82-87.
Gharaibeh S & Mahmoud K. 2013. Decay of maternal antibodies in broiler chickens. Poultry Science, 92: 2333-2336. DOI: 10.3382/ps.2013-03249
Gharaibeh S, Mahmoud K & Al-Natour M. 2008. Field evaluation of maternal antibody transfer to a group of pathogens in meat-type chickens. Poultry Science, 87: 1550-1555. DOI: 10.3382/ps.2008-00119
Gharib HBAA, Mohamed MMA & Haridy FR.AH. 2006. Assessment of booster re-vaccination of grand-parent hens with inactivated vaccine during egg production. Egyptian Poultry Science, 26: 1567-1585.
Grindstaff JL, Brodie ED & Ketterson ED. 2003. Immune function across generations: integrating mechanism and evolutionary process in maternal antibody transmission. Proceedings of the Royal Society of London B: Biological Sciences, 270: 2309-2319. DOI: 10.1098/rspb.2003.2485
Hamal KR, Burgess SC, Pevzner IY & Erf GF. 2006. Maternal antibody transfer from dams to their egg yolks, egg whites, and chicks in meat lines of chickens. Poultry Science, 85: 1364-1372. DOI: 10.1093/ps/85.8.1364
JM S. 2008. Diseases of Poultry (12 ed.): Iowa State University Press, Iowa 50014.
Kapczynski DR, Afonso CL & Miller PJ. 2013.