Effect of Different Levels of Nano-selenium on Performance, Blood Parameters, Immunity and Carcass Characteristics of BroilerChickens

Document Type: Original Paper

Authors

1 1Department of Animal Science, Ilam Branch, Islamic Azad University, Ilam, Iran

2 Department of Animal Science, Rasht Branch, Islamic Azad University, Rasht, Iran

Abstract

The aim of the present study was to test the hypothesis that nano- seleniuminclusion in broilers’ diets can improve productivity and metabolic functions of broilers.Feed and water were provided ad libitum. A total of 180 one-day old male Ross 308 chicks were randomly assigned to six groups based on a completely randomized design, each with three replicates of 10 birds. One of the groups served as the control (CON) and was given a basal diet without further dietary supplementation, whereas the other five groups were offered the same starterandgrower diets further supplemented with dietary nano-selenium (NS) at 0.1 mg/kg of feed (NS1), 0.2 mg/kg of feed (NS2), 0.3 mg/kg of feed (NS3), 0.4 mg/kg of feed (NS4), and 0.5 mg/kg of feed (NS5). Nano-selenium dietary supplementation significantly improved weight gain and feed conversion ratio in starter (1st-21st day), grower (22nd-42nd day) and whole (1st-42nd) periods of experiment (P< 0.05). At the same time, energy and protein utilization was more efficient in NS supplemented groups than the control (P < 0.05). Breast and drumsticks percentages had higher values in the NS supplemented birds than the control (P < 0.05), while abdominal fat percentage had lower values in the NS supplemented birds than the control (P < 0.05).Significant differences in relative weight of testes were observed between treatments (P< 0.05). Glucose and total protein concentrations in blood plasma were not significantly different among the experimental groups (P >0.05). While, albumin levels in blood were decreased and anti-Newcastle disease hemagglutination-inhibition titer was increased after the dietary supplementation with the nano-selenium (P< 0.05). As conclusion, the current study demonstrated that the supplementation of nano-selenium in broiler diets could improve growth performance, carcass components and immune function, without negative effects on internal organs, and other carcass parameters and gastrointestinal parts.

Keywords


Aviagen, 2014. Ross 308 broiler: Nutrition Specification. Aviagen, Scotland, UK.

Aziz-Mousavi SMA, Seidavi AR, Dadashbeiki M, Kilonzo-Nthenge A, Nahashon SN, Laudadio V &Tufarelli V. 2015. Effect of a synbiotic (Biomin®IMBO) on growth performance traits of broiler chickens.European Poultry Science, 79: 1-15. DOI: 10.1399/eps.2015.78

Baylan M, Canogullari S, Ayasan T, &Copur G. 2011. Effects of dietary selenium source, storage time, and temperature on the quality of quail eggs. Biological Trace Element Research, 143: 957-964.DOI: 10.1007/s12011-010-8912-x

Burton RM, Higgins PJ, & McConnell KP. 1977. Reaction of selenium with immunoglobulin molecules. Biochimistry and Biophysics Acta. 493: 323-331.DOI:10.1016/0005-2795(77)90188-X

Cai SJ, Wu CX, Gong LM, Song T, Wu H & Zhang LY. 2012. Effects of nano-selenium on performance, meat quality, immune function, oxidation resistance and tissue selenium content in broilers. Poultry Science, 91: 2532-2539.DOI: 10.3382/ps.2012-02160

Canoğullari S, Ayaşan T, Baylan M, &Çopur G. 2010. The effect of organic selenium on performance characteristics, egg production parameters and egg selenium content of laying Japanese quail.Journal of the Faculty of Veterinary Medicine, Kafkas University, 16: 743-749.

Cao C, Fan R, Chen M, Li X, Xing M, Zhu F, Xue H, Wang K & Xu S. 2017. Inflammatory response occurs in veins of broiler chickens treated with a selenium deficiency diet. Biological Trace Element Research, 173: 1-9.DOI:10.1007/s12011-017-1145-5

Chen G, Wu J & Li C. 2014. Effect of different selenium sources on production performance and biochemical parameters of broilers. Journal of Animal Physiology and Animal Nutrition, 98: 747–754. DOI: 10.1111/jpn.12136

Colnago GL, Jensen LS, & Long PL. 1994. Effect of selenium and vitamin E on the development of immunity to coccidiosis in chickens. Poultry Science, 63: 1136-1143. DOI:10.3382/ps.0631136

Dalia AM, Loh TC, Sazili AQ, Jahromi MF, &Samsudin AA. 2017. The effect of dietary bacterial organic selenium on growth performance, antioxidant capacity, and Selenoproteins gene expression in broiler chickens. BMC Veterinary Research, 13: 254.DOI: 10.1186/s12917-017-1159-4

del Puerto M, Cabrera MC, &Saadoun A. 2017. A note on fatty acids profile of meat from broiler chickens supplemented with inorganic or organic selenium. International Journal of Food Science, 2017: 1-8. DOI: 10.1155/2017/7613069

Dlouha G, Sevcikova S, Dokoupilova A, Zita L, Heindl J, &Skrivan M. 2008. Effect of dietary selenium sources on growth performance, breast muscle selenium, glutathione peroxidase activity and oxidative stability in broilers. Czech Journal of Animal Science, 53: 265-269.

Downs KM, Hess JB&Bilgili SF. 2000. Selenium source effect on broiler carcass characteristics, meat quality and drip loss. Journal of Applied Animal Research, 18: 61–72. DOI: 10.1080/09712119.2000.9706324

Ebrahimi A, Santini A, Alise M, Pourhossein Z, Miraalami N &Seidavi A. 2015. Effect of dried citrus sinensis peel on gastrointestinal microbiota and immune system traits of broiler chickens. Italian Journal of Animal Science, 14: 712-717. DOI: 10.4081/ijas.2015.4194

European Union. 2004. List of the authorized additives in feeding stuffs published in application of Article 9t (b) of Council Directive 70/524/EEC concerning additives in feeding stuffs. Off. J. Eur. Union. C/50:1–144.

Hawkes WC, &Keim NL. 2003. Dietary selenium intake modulates thyroid hormone and energy metabolism in men. The Journal of nutrition, 133: 3443-3448.DOI:10.1093/jn/133.11.3443

HolovskaK, Boldizarova K, Cekonova S, Lenartova V, Levkut M, Javorsky P, &Leng L. 2003. Antioxidant enzyme activities in liver tissue of chickens fed diets supplemented with various forms and amounts of selenium. Journal of Animal and Feed Science. 12: 143-152. DOI: 10.22358/jafs/67691/2003

Hu CH, Li YL, Xiong L, Zhang HM, Song J & Xia MS. 2012. Comparative effects of nano elemental selenium and sodium selenite on selenium retention in broiler chickens. Animal Feed Science and Technology, 177: 204-210. DOI: 10.1016/j.anifeedsci.2012.08.010

Jahanpour H, Seidavi AR, Qotbi AAA, &Payan-Carreira R.2013. Effects of two levels of quantitative feed restriction for a 7- or 14- days period on broilers blood parameters. Acta Scientiae Veterinariae, 41: 1-11.

Konieczka P, Czauderna M, Rozbicka-Wieczorek A, &Smulikowska S. 2015.The effect of dietary fat, vitamin E and selenium concentrations on the fatty acid profile and oxidative stability of frozen stored broiler meat. Journal of Animal and Feed Sciences, 24: 244-251.DOI: 10.22358/jafs/65630/2015

Kuklinski B, Zimmermann R, Ruhlmann C, Nagel R, &Tessmann D. 1991. Tangier disease-a "free radical"- associates disease. Results ofHDL and antioxidant therapy with selenium and D-alpha tocopherol.Zeitschriftfur diegesamteinnereMedizin und ihreGrenzgebiete. 46: 505-511.

Mahmoud H, Ijiri D, Ebeid TA &Ohtsuka A. 2016.Effects of dietary nano-selenium supplementation on growth performance, antioxidative status, and immunity in broiler chickens under thermoneutral and high ambient temperature conditions. The Journal of Poultry Science, 53: 274-283.DOI:10.2141/jpsa.0150133

Moghaddam AZ, Hamzekolaei MM, Khajali F &Hassanpour H. 2017.Role of selenium from different sources in prevention of pulmonary arterial hypertension syndrome in broiler chickens. Biological Trace Element Research, 136: 1-7.DOI: 10.1007/s12011-017-0993-3

Nahavandinejad M, Seidavi A, Asadpour L &Payan-Carreira R. 2014. Blood biochemical parameters of broilers fed differently thermal processed soybean meal. Revista MVZ Córdoba, 19: 4301-4315.

Naik SK, Tiwari SP, Sahu T, Gendley MK, Dutta GK, &Gilhare VR. 2015. Effect of organic selenium and vitamin E supplementation on physico-chemical characteristics of broiler meat. Journal of Animal Research, 5: 617-621.

Payne RL & Southern LL. 2005. Comparison of inorganic and organic selenium sources for broilers. Poultry Science, 84: 898–902.DOI:10.1093/ps/84.6.898

Poorghasemi M, Seidavi AR, Qotbi AAA, Laudadio V &Tufarelli V. 2013. Influence of dietary fat source on growth performance responses and carcass traits of broiler chicks. Asian-Australasian Journal of Animal Sciences, 26: 705-710.DOI:10.5713/ajas.2012.12633

Rajashree K, Muthukumar T, &Karthikeyan N. 2014.Comparative study of the effects of organic selenium on hen performance and productivity of broiler breeders. British Poultry Science, 55: 367-374.DOI:10.1080/00071668.2014.921663

Rao SR, Prakash B, Raju MVLN, Panda AK, Kumari RK, & Reddy EPK. 2016. Effect of supplementing organic forms of zinc, selenium and chromium on performance, anti-oxidant and immune responses in broiler chicken reared in tropical summer. Biological Trace Element Research, 172: 511-520.DOI:10.1007/s12011-015-0587-x

Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, & HoekstraWG. 1973. Selenium: Biochemical role as a component of glutathione peroxidase. Science, 179: 588–590.DOI: 10.1126/science.179.4073.588

Ryu YC, Rhee MS, Lee KM & Kim BC. 2005. Effects of different levels of dietary supplemental selenium om performance, lipid oxidation and color stability of broiler chicks. Poultry Science, 84: 809-815.DOI:10.1093/ps/84.5.809

Seidavi AR, Asadpour L, Dadashbeiki M &Payan-Carreira R. 2014. Effects of dietary fish oil and green tea powder supplementation on broiler chickens immunity. Acta Scientiae Veterinariae, 42: 1-13.

Sevcikova S, Skrivan M, Dlouha G, &Koucky M. 2006.The effect of selenium source on the performance and meat quality of broiler chickens. Czech Journal of Animal Science, 51: 449-457.

Shabani S, Seidavi A, Asadpour L &Corazzin M. 2015.Effects of physical form of diet and intensity and duration of feed restriction on the growth performance, blood variables, microbial flora, immunity, and carcass and organ characteristics of broiler chickens. Livestock Science, 180: 150-157.DOI: 10.1016/j.livsci.2015.07.006

Shen L&Sevanian A. 2001. OxLDL induces macrophage γ-GCS-HS protein expression: a role for oxLDL-associated lipid hydroperoxide in GSH synthesis. Journal of Lipid Research, 42: 813-823.

Shirsat S, Kadam A, Mane RS, Jadhav VV, Zate MK, Naushad M, & Kim KH. 2016. Protective role of biogenic selenium nanoparticles in immunological and oxidative stress generated by enrofloxacin in broiler chicken. Dalton Transactions, 45: 8845-8853.DOI:10.1039/C6DT00120C

SPSS. 1997. SPSS Base 7.5 for Windows. SPSS, Chicago, IL.

Swain BK, Johri TS &Majumdar S. 2000.Effect of supplementation of vitamin E, selenium and their differentcombinations on the performance and immune response of broilers. British Poultry Science, 41: 287-292.DOI:10.1080/713654938

Iizuka Y, Sakurai E & Tanaka Y. 2001. Effect of selenium on serum, hepatic and lipoprotein lipids concentration in rats fed on a high-cholesterol diet. Yakugakuzasshi: Journal of the Pharmaceutical Society of Japan, 121: 93-96. DOI: 10.1248/yakushi.121.93

Van Beirendonck S, Driessen B, Rovers M, Segers L, Ruttens A, & Du Laing G. 2016. Relation between selenomethionine content in dietary selenium sources and selenium deposition in broiler muscle tissue.In The Proceedings of XXV World's Poultry Congress (pp. 63-63).World's Poultry Science Association.

Wang HL, Zhang JS & Yu HQ. 2007. Elemental selenium at nano size possesses lower toxicity without compromising the fundamental effect on selenoenzymes: comparison with selenomethionine in mice. Free Radical Biology and Medicine, 42: 1524-1533.DOI:10.1016/j.freeradbiomed.2007.02.013

Wang Y, Yan X, & Fu L. 2013. Effect of selenium nanoparticles with different sizes in primary cultured intestinal epithelial cells of crucian carp, Carassiusauratusgibelio. International Journal of Nanomedicine, 8: 4007-4013. DOI:10.2147/IJN.S43691

Wang Y. 2009. Differential effects of sodium selenite and nano-Se on growth performance, tissue Se distribution, and glutathione peroxidase activity of avian broiler. Biological Trace Element Research, 128: 184-190.DOI: 10.1007/s12011-008-8264-y

Wang YB & Xu BH. 2008. Effect of different selenium source (sodium selenite and selenium yeast) on broiler chickens. Animal Feed Scienceand Technology, 144: 306-314.DOI:10.1016/j.anifeedsci.2007.10.012

Zhang JL, Xu B, Huang X D, Gao YH, Chen Y & Shan AS. 2016. Selenium deficiency affects the mRNA expression of inflammatory factors and selenoprotein genes in the kidneys of broiler chicks. Biological Trace Element Research, 171: 201-207.DOI: 10.1007/s12011-015-0512-3

Zhang JS, Wang XF, & Xu TW. 2008. Elemental selenium at nano size (nano-Se) as a potential chemopreventive agent with reduced risk of selenium toxicity: Comparison with Se-methylselenocysteinein mice. Toxicological Science, 101: 22–31.DOI:10.1093/toxsci/kfm221

Zhang Z, Liu M, Guan Z, Yang J, Liu Z, & Xu S. 2017. Disbalance of calcium regulation-related genes in broiler hearts induced by selenium deficiency. Avian Pathology, 46: 265-271.DOI:10.1080/03079457.2016.1259528

Zhou X & Wang Y. 2011. Influence of dietary nano elemental selenium on growth performance, tissue selenium distribution, meat quality, and glutathione peroxidase activity in Guangxi Yellow chicken. Poultry Science, 90: 680-686.DOI:10.3382/ps.2010-00977